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Statin Side Effects

Meaning

Statin Side Effects represent the spectrum of adverse physiological reactions that may occur following the therapeutic administration of HMG-CoA reductase inhibitors, commonly known as statins. These effects range in severity from the frequently reported, mild muscle aches (myalgia) to rare, but serious, conditions like rhabdomyolysis and the potential for new-onset diabetes mellitus. A significant concern within the hormonal health domain is the potential for statins to interfere with the mevalonate pathway, which is the foundational biosynthetic route for all endogenous steroid hormones. Clinical monitoring is essential to balance lipid benefits against potential risks.