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Spironolactone

Meaning

Spironolactone is a pharmaceutical agent classified primarily as a potassium-sparing diuretic, but its significant clinical utility in hormonal health stems from its function as a non-selective aldosterone antagonist and, crucially, a potent anti-androgen. In endocrine practice, it is frequently prescribed to manage conditions associated with androgen excess, such as hirsutism, acne, and female pattern hair loss, by blocking the action of androgens at the receptor level. This compound offers a targeted approach to mitigating the peripheral effects of elevated or hyper-responsive androgen signaling, particularly in women.