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Spermatogenic Arrest

Meaning

Spermatogenic Arrest is a pathological condition within male reproductive health defined by the complete or partial cessation of spermatogenesis, the intricate process of sperm production, at a specific, identifiable stage of germ cell development within the seminiferous tubules of the testes. This profound arrest results in a severe deficiency or the total absence of mature spermatozoa in the ejaculate, clinically manifesting as non-obstructive azoospermia or severe oligozoospermia. Precise histological identification of the exact stage of arrest is clinically critical for accurately diagnosing the underlying etiology and for guiding the selection of potential therapeutic or fertility-preserving interventions.