A broad classification encompassing peptides, small proteins, and other bioactive compounds that function as precise messengers within the body, regulating specific cellular activities and systemic functions, often in a paracrine or endocrine manner. These molecules are distinguished by their high receptor specificity and potent biological effects at low concentrations. Clinical use involves their targeted introduction to fine-tune complex physiological processes.
Origin
This is a descriptive term derived from molecular biology and pharmacology, emphasizing the highly specific nature of these biological agents compared to general hormones or nutrients. The concept is rooted in the discovery of peptide hormones and growth factors, which act as highly specialized signals. The term is used in clinical practice to denote advanced, targeted therapeutic agents.
Mechanism
These molecules operate by binding to specific, high-affinity receptors on the surface of target cells, initiating a cascade of intracellular events known as signal transduction. This mechanism allows for a highly localized and precise physiological response, such as promoting collagen synthesis, stimulating cell differentiation, or modulating immune function. Their specialization minimizes off-target effects, making them valuable tools for targeted tissue remodeling and functional enhancement.
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