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Spatial Cognition

Meaning

The complex set of mental processes responsible for acquiring, storing, manipulating, and recalling information about the spatial environment, including navigation, object localization, and mental mapping. This critical cognitive domain relies heavily on the integrity of brain regions such as the hippocampus, which is particularly sensitive to hormonal fluctuations. Optimal spatial cognition is closely linked to balanced neurosteroid levels, including estrogen and testosterone. Declines in this function can be an early indicator of neuroendocrine changes.