The clinical focus on sustaining the capacity to mentally manipulate two- or three-dimensional objects and navigate environments accurately as an individual ages. This function relies heavily on the integrity of parietal and hippocampal structures. Maintenance aims to preserve this visuospatial processing capacity.
Origin
This term originates in neuropsychology, where spatial cognition is assessed as a distinct cognitive domain often affected by aging or specific neurological insults. Maintenance addresses the physical substrates supporting this ability.
Mechanism
Maintaining spatial acuity is supported by ensuring robust cerebral perfusion and reducing the burden of neuroinflammation which can degrade white matter tracts connecting spatial processing centers. Adequate sex steroid levels, particularly estrogen in certain contexts, support dendritic spine density in relevant cortical areas. Interventions that promote cerebral blood flow are therefore instrumental in this preservation effort.
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