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SPARC

Meaning

In the context of endocrinology and cellular biology, SPARC is an acronym for Secreted Protein Acidic and Rich in Cysteine, a matricellular glycoprotein that plays a crucial regulatory role in tissue remodeling, cell-matrix interactions, and various pathological processes. This protein is involved in modulating cell proliferation, adhesion, and migration, and its expression is often dysregulated in conditions such as fibrosis, cancer, and metabolic syndrome. Its function as a biological signaling molecule makes it a key target in understanding the intersection of cellular environment and systemic health.