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Somatotropin Axis Modulation

Meaning

Somatotropin Axis Modulation is the clinical practice of selectively adjusting the function of the Somatotropin axis, which comprises the Hypothalamus, Pituitary Gland, and the target tissues that respond to Growth Hormone (GH) and Insulin-like Growth Factor 1 (IGF-1). This modulation is utilized to optimize body composition, enhance metabolic function, and support tissue repair, particularly in cases of Age-Related Growth Hormone Deficiency (AGHD). Strategies involve using growth hormone secretagogues or, in specific clinical scenarios, direct hormone replacement to restore physiological signaling. The aim is to move beyond mere deficiency correction to achieve functional optimization.