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Somatotropic Axis Refinement

Meaning

Somatotropic Axis Refinement is a clinical and physiological objective focused on optimizing the complex neuroendocrine system comprising Growth Hormone-Releasing Hormone (GHRH), Growth Hormone (GH), and Insulin-like Growth Factor 1 (IGF-1). This refinement involves strategic interventions to restore the youthful, pulsatile secretion pattern of GH, which naturally declines with age, thereby supporting metabolic health, body composition, and tissue regeneration. The goal is to maximize the anabolic and lipolytic effects of the axis in a physiologically sound and non-suppressive manner.