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Somatotropic Axis Preservation

Meaning

Clinical strategies dedicated to maintaining the optimal function and signaling fidelity of the growth hormone (GH) axis, encompassing the hypothalamus, pituitary, and peripheral targets like the liver. Preservation focuses on ensuring adequate pulsatile GH secretion and subsequent appropriate Insulin-like Growth Factor 1 (IGF-1) generation, which is vital for body composition, bone health, and cellular repair throughout adulthood. We actively seek to mitigate age-related decline in this system.