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Somatopause Mitigation Science

Meaning

Somatopause mitigation science is the specialized field of research and clinical practice dedicated to counteracting the physiological decline associated with somatopause, which is the age-related reduction in the pulsatile secretion of growth hormone (GH) and its downstream mediator, Insulin-like Growth Factor 1 (IGF-1). The goal of mitigation is to restore a more youthful somatotropic axis function to improve body composition, enhance vitality, and support tissue regeneration. This science explores various therapeutic modalities, including secretagogues and lifestyle interventions, to address the profound metabolic and functional changes that accompany this decline. Effective mitigation aims to slow the sarcopenia and central adiposity that often characterize aging.