The clinical strategy of strengthening the physical, structural, and cellular resilience of the body, specifically targeting musculoskeletal tissue, connective tissue, and cellular membranes against degradation and injury. This ‘fortification’ is a measure of the body’s resistance to age-related frailty and systemic damage. It is intrinsically linked to the efficacy of anabolic hormones and nutritional status.
Origin
This term combines the Greek root soma (body) with the clinical goal of ‘fortification,’ emphasizing a proactive approach to maintaining structural health. It is a concept derived from gerontology and regenerative medicine, which seeks to counteract the inevitable catabolic processes of aging. The focus on integrity highlights the importance of quality and function over mere mass.
Mechanism
Fortification is achieved through the optimal signaling of anabolic hormones, particularly growth hormone, insulin-like growth factor 1 (IGF-1), and testosterone, which drive protein synthesis and collagen production in bone and connective tissue. It also relies on maintaining robust cellular membrane health through adequate lipid and antioxidant support. The mechanism is a continuous, hormonally-driven process of repair and regeneration that ensures the structural components of the body remain robust and functional under stress.
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