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Somatic Information Fidelity

Meaning

Somatic Information Fidelity refers to the high degree of accuracy and integrity maintained during the transmission, storage, and expression of genetic and epigenetic information within the body’s non-reproductive (somatic) cells. High fidelity ensures that cells correctly execute their functional programs, resisting errors that lead to senescence, malignant transformation, or age-related dysfunction. This concept is fundamentally linked to the efficiency of DNA repair mechanisms, the stability of telomeres, and the precision of the epigenetic landscape. Optimal hormonal status is a key factor in preserving this cellular accuracy.