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Somatic Code Refactoring

Meaning

Somatic Code Refactoring is a conceptual term in advanced longevity research, referring to the process of experimentally or therapeutically reprogramming the epigenetic landscape of a terminally differentiated somatic cell. This refactoring aims to reverse or reset the accumulated age-related changes in gene expression without altering the underlying DNA sequence. The goal is to restore a more youthful, resilient, and pluripotent-like cellular state, thereby combating cellular senescence and tissue dysfunction that contribute to biological aging. It is a bold theoretical approach to extending healthspan by manipulating the heritable molecular signature of cells.