What is the Origin of Solar Lentigines?

The term combines "solar," relating to the sun, with lentigo, a Latin word for "lentil," referring to their small, flat, brown appearance. They are a common dermatological finding, clearly distinguishing them from freckles by their persistence in the absence of sun exposure. Their prevalence increases significantly with age.

What is the Mechanism of Solar Lentigines?

While primarily triggered by chronic ultraviolet radiation exposure, the formation of solar lentigines can be modulated by hormonal factors. Estrogen and Progesterone receptors are present on melanocytes, and hormonal fluctuations can increase the sensitivity of these cells to UV-induced damage and hyperpigmentation. This hormonal influence, coupled with photo-aging, exacerbates the localized overproduction of melanin, leading to the clinical manifestation of these spots.

Solar Lentigines ∞ Area

Solar Lentigines

Meaning

Solar lentigines are benign, circumscribed pigmented macules, commonly known as liver spots or age spots, that appear on sun-exposed areas of the skin, such as the face, hands, and décolletage. Histologically, they are characterized by a localized proliferation of melanocytes and an increased accumulation of melanin in the basal layer of the epidermis. They are a definitive clinical marker of cumulative photodamage.