The temporally organized pattern of an individual’s daily cycles of alertness and rest, fundamentally dictated by the synchronization of the central circadian pacemaker with environmental light-dark cycles.
Origin
This term comes from chronobiology, describing the external manifestation of the body’s internal timing mechanisms. Its adherence is crucial for regulating systemic physiological rhythms.
Mechanism
The schedule dictates the timing of melatonin secretion from the pineal gland and the subsequent nadir of core body temperature, signaling the body for rest. Proper alignment ensures that anabolic processes, including growth hormone release and cellular repair, occur during the nocturnal phase. Inconsistencies directly impair the feedback loops governing the HPA axis, leading to chronic stress signaling.
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