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Sleep-Wake Cycle Modulation

Meaning

Sleep-Wake Cycle Modulation is the clinical application of interventions designed to precisely regulate the body’s intrinsic circadian rhythm, the approximate 24-hour cycle governing periods of sleep and wakefulness. Effective modulation involves optimizing exposure to light, timing of meals, physical activity, and targeted hormonal or nutritional support to synchronize the endogenous biological clock with the external environment. This synchronization is paramount for hormonal health, as the secretion of key hormones like cortisol and melatonin is strictly time-dependent. It is a fundamental strategy for improving systemic physiological function.