Skip to main content

Sleep-Related Hormonal Dysregulation

Meaning

Sleep-related hormonal dysregulation describes a complex clinical state where the normal, rhythmic, and often pulsatile secretion patterns of key endocrine hormones are pathologically altered due to chronic sleep disturbances, insufficient sleep duration, or an underlying sleep disorder. This bidirectional imbalance impacts the crucial regulatory axes of the body, affecting the nocturnal release of growth hormone, the circadian rhythm of cortisol, and the balance of metabolic hormones like ghrelin and leptin. Addressing underlying sleep quality is therefore an integral and necessary component of comprehensive hormonal and metabolic health management.