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Sleep Pressure Titration

Meaning

Sleep Pressure Titration is the biological and clinical process of precisely adjusting the accumulated need for sleep, known as homeostatic sleep drive or sleep pressure, to achieve an optimal and restorative sleep episode. This process involves the controlled build-up and subsequent release of sleep-inducing neurochemicals, such as adenosine, during wakefulness. Clinically, this term is used to describe strategies, often behavioral, that manipulate wake duration to optimize sleep onset and quality. The correct titration is essential for maximizing deep sleep.