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Sleep Phase Regulation

Meaning

Sleep Phase Regulation is the precise, intricate neuroendocrine control over the timing of an individual’s sleep onset and offset, ensuring that the main sleep period aligns optimally with the body’s internal biological night. This critical regulation is primarily governed by the dynamic interaction between the homeostatic sleep drive and the powerful circadian alerting signal, with the ultimate goal of maximizing restorative sleep quality and duration. Significant dysregulation of the sleep phase is a common hallmark of many sleep disorders and is inextricably linked to underlying hormonal and metabolic imbalance.