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Sleep Hormone Interplay

Meaning

Sleep Hormone Interplay describes the complex, bidirectional signaling network between the endocrine system and the sleep-wake cycle, where specific hormones regulate sleep architecture and, conversely, sleep quality dictates the optimal pulsatile release of key hormones. This intricate balance involves neurohormones like melatonin and adenosine, as well as systemic hormones such as cortisol, growth hormone, and the appetite regulators leptin and ghrelin. Disruption of this interplay leads to a cascade of negative metabolic, immune, and cognitive consequences, underscoring the absolute necessity of high-quality, synchronized sleep for hormonal homeostasis and overall wellness.