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Sleep Deprivation Damage Multiplier

Meaning

A clinical concept describing the exponential increase in physiological and cellular damage that occurs when chronic or acute sleep deprivation co-occurs with other systemic stressors, such as high systemic inflammation or hormonal dysregulation. Sleep loss does not merely add damage; it significantly amplifies the negative impact of pre-existing health issues, accelerating biological aging and increasing the risk of metabolic and cognitive disorders. This effect underscores the non-linear importance of restorative sleep.