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Sleep-Dependent Metabolism

Meaning

Sleep-Dependent Metabolism describes the unique and essential set of catabolic and anabolic biochemical processes that are actively regulated and optimized by the specific stages and timing of the nightly sleep cycle. This metabolic shift includes the nocturnal suppression of appetite-stimulating hormones like ghrelin, the critical peak release of Growth Hormone, and a significant change in glucose utilization and insulin sensitivity. Optimal sleep is therefore not a passive state but a required metabolic engine for repair, detoxification, and the maintenance of a healthy body composition and endocrine profile. Disruption of this process is a primary driver of insulin resistance and weight gain.