What is the Origin of Sleep and Insulin Sensitivity?

This concept originates in metabolic endocrinology, where studies demonstrate acute and chronic sleep restriction elevates metabolic risk factors. The circadian timing of meals and sleep significantly affects glucose handling.

What is the Mechanism of Sleep and Insulin Sensitivity?

Sleep restriction acutely increases sympathetic nervous system outflow and elevates counter-regulatory hormones like cortisol and growth hormone. These factors antagonize insulin action by promoting hepatic glucose output and reducing glucose uptake efficiency in skeletal muscle. Therefore, poor sleep forces the pancreas to overwork to maintain euglycemia.

Sleep and Insulin Sensitivity

Meaning

Sleep and Insulin Sensitivity defines the crucial link between the quantity and quality of nocturnal rest and the body’s responsiveness to the metabolic hormone insulin. Insufficient sleep consistently impairs glucose homeostasis by inducing peripheral insulin resistance. This relationship directly impacts long-term metabolic health.