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SLCO2B1

Meaning

SLCO2B1 stands for Solute Carrier Organic Anion Transporter Family Member 2B1, which is a specific gene that encodes a critical membrane transport protein. This protein is fundamentally responsible for the cellular uptake of a diverse array of compounds, including conjugated steroid hormone metabolites, certain bile acids, and a variety of pharmaceutical drugs. In the context of hormonal health, common genetic variations in the SLCO2B1 gene can significantly alter the body’s clearance rate and systemic exposure to hormone metabolites, thereby impacting overall hormonal balance and the required dosage for therapeutic regimens.