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SLC22A1

Meaning

SLC22A1 is the official gene symbol for the Solute Carrier Family 22 Member 1 protein, which is an important transmembrane transporter protein clinically known as Organic Cation Transporter 1 (OCT1). This protein is predominantly expressed on the sinusoidal membrane of hepatocytes in the liver, playing a critical role in the uptake of various endogenous organic cations and numerous clinically relevant drugs. Genetic variations in this gene can significantly impact drug efficacy and safety.