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Skin Regeneration

Meaning

Skin regeneration is the complex biological process by which damaged or lost skin tissue is replaced with new, functional tissue, restoring the structural integrity and barrier function of the integumentary system. This process involves a highly coordinated cascade of cellular events, including inflammation, proliferation, and tissue remodeling, executed by keratinocytes, fibroblasts, and immune cells. Hormones, growth factors, and peptides are essential modulators of skin regeneration, influencing collagen synthesis, angiogenesis, and cell migration. Successful regeneration minimizes scarring and maintains the skin’s protective and sensory roles.