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Skeletal Muscle Glucose Uptake

Meaning

Skeletal Muscle Glucose Uptake is the physiological process by which glucose, the body’s primary energy substrate, is transported from the bloodstream across the cell membrane into the skeletal muscle cells. This uptake is primarily mediated by the glucose transporter GLUT4 and is significantly stimulated by the action of insulin and muscle contraction. Efficient glucose uptake is absolutely fundamental for maintaining euglycemia, providing necessary energy for physical activity, and preventing the chronic hyperglycemia characteristic of insulin resistance and type 2 diabetes.