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Sirtuin Function Modulation

Meaning

Sirtuin function modulation refers to the deliberate therapeutic or nutritional alteration of the enzymatic activity of Sirtuins, a class of NAD+-dependent deacetylases that govern cellular response to metabolic stress and are central to longevity pathways. In hormonal health, this modulation aims to enhance cellular repair, improve mitochondrial function, and regulate key metabolic hormones like insulin and adiponectin. It represents a cutting-edge strategy for promoting systemic health and anti-aging. The activity of these enzymes is a direct link between nutrition and gene expression.