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Single-Cell Sequencing

Meaning

Single-cell sequencing is a highly sophisticated and revolutionary molecular technique that enables the isolation and detailed genetic analysis of individual cells, providing an unprecedented, high-resolution view of cellular heterogeneity within a complex tissue or cell population. This advanced methodology allows researchers to precisely determine the DNA, RNA, or epigenetic profile of one single cell, clearly distinguishing it from its numerous neighbors. In the field of endocrinology, this precision is invaluable for identifying rare, functionally distinct hormone-secreting cell types within endocrine glands and for accurately characterizing the transcriptional landscape of specific tumor cells.