A category of clinical interventions that utilizes endogenous or modified biochemical messengers—including hormones, peptides, cytokines, and growth factors—to correct communication errors and restore optimal function within biological systems. These therapeutics are designed to act with high specificity on target receptors, aiming to fine-tune cellular responses and promote regenerative processes. This represents a modern, targeted approach to managing complex physiological dysfunctions.
Origin
This term stems from pharmacology and molecular biology, where the focus is on the intricate network of cellular communication. The use of “therapeutics” emphasizes the deliberate, clinical application of these molecules to achieve a measurable health outcome, often in the domains of longevity and metabolic health.
Mechanism
The mechanism involves administering molecules that either replenish a deficient signal, block an excessive or inappropriate signal, or amplify a necessary but weak signal. For example, growth factors can stimulate tissue repair, while certain peptides can modulate appetite or metabolic rate. These agents interact with cell surface or intracellular receptors to initiate a precise signal transduction cascade, correcting systemic imbalances at the cellular level.
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