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SHBG Management

Meaning

A clinical strategy focused on modulating the concentration of Sex Hormone-Binding Globulin (SHBG), a liver-produced glycoprotein that binds and inactivates sex hormones, primarily testosterone and estradiol. Effective management involves therapeutic interventions, often nutritional or pharmacological, designed to raise or lower SHBG levels to optimize the ratio of free (biologically active) to bound hormones. This management is essential for ensuring target tissues receive adequate hormonal signaling.