SHBG Management Strategy

Meaning

SHBG Management Strategy is the clinical approach focused on modulating the concentration and activity of Sex Hormone Binding Globulin (SHBG), a glycoprotein primarily produced by the liver that binds and transports sex hormones like testosterone and estradiol. Since only the ‘free,’ unbound fraction of these hormones is biologically active, managing SHBG levels is crucial for optimizing the functional availability of sex steroids to target tissues. Dysregulation of SHBG can lead to symptoms of hormonal excess or deficiency.

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