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SHBG Index Monitoring

Meaning

SHBG Index Monitoring is the clinical practice of tracking and interpreting the calculated ratio or derived index involving Sex Hormone Binding Globulin (SHBG) and total hormone concentrations, such as the Free Androgen Index (FAI). SHBG is a critical glycoprotein that binds sex hormones, primarily testosterone and estradiol, thereby regulating their bioavailability. Monitoring this index provides a surrogate measure of the biologically active, unbound hormone fraction, which is vital for assessing androgen and estrogen status in both males and females.