SHBG Binding Capacity is the quantitative measure of the maximum amount of sex hormone-binding globulin available to bind and transport sex steroids, primarily testosterone and estradiol, in the circulation.
Origin
This measurement is a standard component of comprehensive endocrine panels, reflecting the liver’s synthetic function and hormonal milieu.
Mechanism
The capacity directly influences the fraction of free, biologically active hormone available to target tissues; high binding capacity reduces free hormone availability, while low capacity increases it.
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