A quantifiable set of biochemical indicators, including sex hormones, their metabolites, pituitary regulators, and associated metabolic factors, used to objectively assess and monitor the physiological status of reproductive and sexual function. These biomarkers provide a clinical window into libido, erectile function, menstrual cycle health, and fertility potential. Comprehensive analysis moves beyond simple total hormone levels to include free fractions and critical ratios.
Origin
A clinical term combining sexual health, the state of physical, emotional, and social well-being in relation to sexuality, with biomarkers, the measurable indicators of a biological state. It represents the objective, laboratory-based assessment of a deeply personal health domain.
Mechanism
Key biomarkers include total and free testosterone, estrogen fractions (E1, E2, E3), Progesterone, Luteinizing Hormone (LH), Follicle-Stimulating Hormone (FSH), and Sex Hormone Binding Globulin (SHBG). The interpretation focuses on the delicate interplay between the HPG axis and peripheral hormones. For example, a high SHBG can bind free testosterone, reducing biological activity despite a normal total level, illustrating the need for comprehensive testing.
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