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Sex Hormone Ablation

Meaning

Sex Hormone Ablation is a critical therapeutic strategy involving the complete or near-complete suppression of the production or action of endogenous sex steroid hormones, such as testosterone or estrogen, which is frequently utilized in the clinical management of hormone-sensitive cancers. This potent intervention is achieved through surgical removal of the hormone-producing gonads or the use of powerful pharmaceutical agents that block hormone synthesis or prevent receptor binding. The fundamental goal is to eliminate the necessary hormonal stimulus that is driving the proliferation of malignant cancer cells, thereby achieving disease remission or stabilization.