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Serum Vs Saliva Testing

Meaning

Serum Vs Saliva Testing is a comparative clinical evaluation of two distinct methodologies for measuring hormone levels, each offering a unique perspective on the body’s endocrine status. Serum testing, the conventional gold standard, measures the total concentration of hormones, including the fraction bound to carrier proteins and the free fraction. Saliva testing, conversely, measures only the free, or bioavailable, fraction of steroid hormones that is readily accessible to target tissues. The choice between these two methods depends on the clinical question, the specific hormone being measured, and the need for dynamic versus static assessment.