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Serotonin-Melatonin Pathway

Meaning

The Serotonin-Melatonin Pathway describes the specific, two-step biochemical cascade primarily localized within the pineal gland, where the neurotransmitter serotonin is metabolically converted into the hormone melatonin. This pathway is a central regulator of the body’s circadian rhythm, directly controlling the timing of the sleep-wake cycle and influencing seasonal biological processes. Clinically, the efficient function of this neuroendocrine sequence is indispensable for regulating sleep quality, stabilizing mood, and maintaining overall systemic health.