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Serotonin Dopamine

Meaning

A reference to the critical, reciprocal interplay between the two major monoamine neurotransmitter systems, serotonin (5-HT) and dopamine (DA), which collectively regulate mood, motivation, reward processing, executive function, and motor control. Their balanced activity is essential for emotional stability and goal-directed behavior. Dysregulation in their interaction is implicated in various neuropsychiatric conditions.