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Serotonergic Systems

Meaning

The network of neurons, receptors, and transporters within the central and peripheral nervous systems that utilize the monoamine neurotransmitter serotonin (5-hydroxytryptamine or 5-HT) for chemical signaling. These systems are fundamentally involved in regulating a broad spectrum of physiological functions, including mood, sleep, appetite, and gut motility. The functional integrity of the serotonergic systems is paramount for psychological well-being and neuroendocrine balance.