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Senolytic Therapy Exploration

Meaning

Senolytic Therapy Exploration is the clinical and scientific investigation into compounds or strategies designed to selectively induce apoptosis, or programmed cell death, in senescent cells—cells that have ceased dividing but remain metabolically active and secrete pro-inflammatory factors. The exploration aims to reduce the body’s senescent cell burden, thereby mitigating the chronic, low-grade inflammation (senescence-associated secretory phenotype or SASP) that drives tissue aging and dysfunction. This is a cutting-edge approach to extending healthspan and improving tissue resilience.