What is the Origin of Senolytic Support Peptides?

This term is a recent construct, combining the molecular entity "peptide" with the pharmacological concept of "senolytics," which are agents that selectively kill senescent cells. The development of these compounds stems from breakthroughs in cellular gerontology and the understanding that senescent cell accumulation is a primary driver of age-related disease.

What is the Mechanism of Senolytic Support Peptides?

The mechanism of action involves the peptide selectively targeting anti-apoptotic pathways that senescent cells rely on for survival. By disrupting these pathways, the peptide forces the senescent cell to undergo apoptosis, a controlled cellular suicide. Once cleared, the body's natural repair mechanisms can replace the space with healthy, functional cells. This targeted clearance mechanism reduces the burden of the Senescence-Associated Secretory Phenotype (SASP), thereby dampening systemic inflammation and rejuvenating the tissue microenvironment.

Senolytic Support Peptides ∞ Area

Senolytic Support Peptides

Meaning

Senolytic Support Peptides are a specialized class of molecular instruction peptides designed to selectively induce apoptosis, or programmed cell death, in senescent cells—cells that have ceased dividing but remain metabolically active and secrete pro-inflammatory signals. These peptides function as targeted therapeutic agents to clear these dysfunctional, “zombie-like” cells, thereby reducing the chronic systemic inflammation and tissue damage they cause. Clinically, their application is a key strategy in longevity medicine for improving tissue microenvironments, promoting regeneration, and reversing hallmarks of biological aging. They represent a novel, highly specific approach to cellular detoxification.