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Senolytic Peptides

Meaning

Senolytic Peptides are a class of short-chain amino acids or peptide-based compounds designed to selectively induce apoptosis, or programmed cell death, in senescent cells. These are cells that have ceased dividing but remain metabolically active and secrete pro-inflammatory factors, known as the Senescence-Associated Secretory Phenotype (SASP). These compounds target the survival pathways of these “zombie cells,” which accumulate with age and contribute significantly to tissue dysfunction, chronic inflammation, and the pathology of aging. In hormonal health, their use is a cutting-edge strategy to reduce the systemic inflammatory burden, thereby improving endocrine function and target tissue responsiveness.