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Senescence Performance Deficit

Meaning

Senescence Performance Deficit is a clinical descriptor for the quantifiable decline in functional capacity and physiological resilience that occurs as cells and tissues accumulate senescent markers with advancing chronological age. This deficit is characterized by reduced cellular energy production, impaired tissue repair mechanisms, and a chronic pro-inflammatory state, collectively known as “inflammaging.” It represents the measurable gap between an individual’s current functional status and their youthful potential.