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Senescence Mitigation

Meaning

A therapeutic strategy aimed at reducing the burden of senescent cells—aged, dysfunctional cells that cease dividing but remain metabolically active and secrete pro-inflammatory factors—within tissues. This mitigation process seeks to improve tissue function, reduce chronic low-grade inflammation, and slow the overall rate of biological aging. It is a key intervention target in geroscience, moving beyond symptom management to address a root cause of age-related decline.