Self-Regulation Capacity refers to the integrated physiological ability of the body, primarily through the autonomic nervous system and endocrine feedback loops, to maintain internal stability (allostasis) despite external perturbations. This capacity reflects the robustness of systems like the HPA axis in managing stress response and energy mobilization effectively. High capacity correlates with greater resilience to metabolic challenge.
Origin
The concept originates from general systems theory and physiology, where homeostasis is the ideal, but allostasis—regulated change—is the functional reality managed by self-regulating mechanisms. In hormonal health, it specifically describes the inherent feedback strength of endocrine axes.
Mechanism
The mechanism relies on precise negative and positive feedback loops. For instance, adequate cortisol levels trigger a downregulation of CRH and ACTH release from the hypothalamus and pituitary, respectively, thus self-limiting the stress response. Similarly, high circulating insulin signals the pancreas to reduce further secretion. Protocols aim to strengthen these inherent feedback loops, often by reducing chronic inflammatory load that otherwise dampens receptor sensitivity.
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