The systematic, iterative process of applying scientific principles, data feedback, and targeted interventions to enhance an individual’s physiological and psychological performance metrics. This field integrates diagnostics from endocrinology, genetics, and metabolism to achieve measurable improvements in healthspan and function. It treats the self as a continuously improvable biological system.
Origin
This concept draws from the modern self-improvement movement but grounds it rigorously in measurable biological outcomes, contrasting with subjective wellness goals. Science emphasizes the empirical, testable nature of the optimization protocols.
Mechanism
Optimization relies on creating controlled perturbations—such as targeted fasting or specific hormone modulation—and measuring the systemic response via biomarkers. By analyzing data from axes like the HPA or HPG, interventions are refined to push physiological set points toward maximal efficiency. This feedback loop ensures interventions are personalized and effective for the individual’s unique biology.
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