Skip to main content

Selective Secretagogue Action

Meaning

Selective secretagogue action refers to the precise pharmacological property of an agent that specifically stimulates the secretion of one particular hormone or a narrow group of hormones from an endocrine gland, while exhibiting minimal or negligible effect on the release of other, unrelated hormones. This targeted action is highly valued in clinical endocrinology, as it permits the focused modulation of a single hormonal axis, such as the growth hormone axis, without inducing unwanted side effects from non-specific stimulation of other pituitary or peripheral hormones. It represents a high degree of pharmacodynamic specificity.