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Selective Reduction

Meaning

Selective Reduction, in the context of advanced hormonal and metabolic health, refers to a highly targeted therapeutic strategy designed to diminish the concentration or biological activity of a single, specific molecular target or metabolite while leaving related compounds unaffected. This clinical precision is sought to achieve a specific outcome, such as the targeted reduction of an undesirable estrogen metabolite like 16α-hydroxyestrone or the precise down-regulation of a single inflammatory pathway. The goal is to maximize therapeutic benefit by minimizing off-target effects and maintaining the integrity of the broader endocrine milieu.